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Ca(2+)-calmodulin inhibits tail-anchored protein insertion into the mammalian endoplasmic reticulum membrane

Cytosolic components and pathways have been identified that are involved in inserting tail-anchored (TA) membrane proteins into the yeast or mammalian endoplasmic reticulum (ER) membrane. Searching for regulatory mechanisms of TA protein biogenesis, we found that Ca(2+)-calmodulin (CaM) inhibits the...

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Detalles Bibliográficos
Autores principales: Haßdenteufel, Sarah, Schäuble, Nico, Cassella, Patrizia, Leznicki, Pawel, Müller, Anika, High, Stephen, Jung, Martin, Zimmermann, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884127/
https://www.ncbi.nlm.nih.gov/pubmed/22001204
http://dx.doi.org/10.1016/j.febslet.2011.10.008