Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors

Acidic tissue microenvironment contributes to tumor progression via multiple effects including the activation of angiogenic factors and proteases, reduced cell-cell adhesion, increased migration and invasion, etc. In addition, intratumoral acidosis can influence the uptake of anticancer drugs and mo...

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Detalles Bibliográficos
Autores principales: Sedlakova, Olga, Svastova, Eliska, Takacova, Martina, Kopacek, Juraj, Pastorek, Jaromir, Pastorekova, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884196/
https://www.ncbi.nlm.nih.gov/pubmed/24409151
http://dx.doi.org/10.3389/fphys.2013.00400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884196/
https://www.ncbi.nlm.nih.gov/pubmed/24409151
http://dx.doi.org/10.3389/fphys.2013.00400

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