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Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors
Acidic tissue microenvironment contributes to tumor progression via multiple effects including the activation of angiogenic factors and proteases, reduced cell-cell adhesion, increased migration and invasion, etc. In addition, intratumoral acidosis can influence the uptake of anticancer drugs and mo...
Autores principales: | Sedlakova, Olga, Svastova, Eliska, Takacova, Martina, Kopacek, Juraj, Pastorek, Jaromir, Pastorekova, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884196/ https://www.ncbi.nlm.nih.gov/pubmed/24409151 http://dx.doi.org/10.3389/fphys.2013.00400 |
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