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Convergence of dopamine and glutamate signaling onto striatal ERK activation in response to drugs of abuse

Despite their distinct targets, all addictive drugs commonly abused by humans evoke increases in dopamine (DA) concentration within the striatum. The main DA Guanine nucleotide binding protein couple receptors (GPCRs) expressed by medium-sized spiny neurons of the striatum are the D1R and D2R, which...

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Detalles Bibliográficos
Autores principales: Cahill, Emma, Salery, Marine, Vanhoutte, Peter, Caboche, Jocelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884214/
https://www.ncbi.nlm.nih.gov/pubmed/24409148
http://dx.doi.org/10.3389/fphar.2013.00172