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Evolutionary and ontogenetic changes in RNA editing in human, chimpanzee, and macaque brains

Adenosine-to-inosine (A-to-I) substitutions are the most common type of RNA editing in mammals. A-to-I RNA editing is particularly widespread in the brain and is known to play important roles in neuronal functions. In this study we investigated RNA-editing changes during human brain development and...

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Detalles Bibliográficos
Autores principales: Li, Zhongshan, Bammann, Hindrike, Li, Mingshuang, Liang, Hongyu, Yan, Zheng, Phoebe Chen, Yi-Ping, Zhao, Min, Khaitovich, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884655/
https://www.ncbi.nlm.nih.gov/pubmed/24152549
http://dx.doi.org/10.1261/rna.039206.113