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Probing N(6)-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA

N(6)-methyladenosine (m(6)A) is the most abundant modification in mammalian mRNA and long noncoding RNA (lncRNA). Recent discoveries of two m(6)A demethylases and cell-type and cell-state-dependent m(6)A patterns indicate that m(6)A modifications are highly dynamic and likely play important biologic...

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Detalles Bibliográficos
Autores principales: Liu, Nian, Parisien, Marc, Dai, Qing, Zheng, Guanqun, He, Chuan, Pan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884656/
https://www.ncbi.nlm.nih.gov/pubmed/24141618
http://dx.doi.org/10.1261/rna.041178.113