Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs

The mechanisms of gene expression regulation by miRNAs have been extensively studied. However, the regulation of miRNA function and decay has long remained enigmatic. Only recently, 3′ uridylation via LIN28A-TUT4/7 has been recognized as an essential component controlling the biogenesis of let-7 miR...

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Detalles Bibliográficos
Autores principales: Ustianenko, Dmytro, Hrossova, Dominika, Potesil, David, Chalupnikova, Katerina, Hrazdilova, Kristyna, Pachernik, Jiri, Cetkovska, Katerina, Uldrijan, Stjepan, Zdrahal, Zbynek, Vanacova, Stepanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884668/
https://www.ncbi.nlm.nih.gov/pubmed/24141620
http://dx.doi.org/10.1261/rna.040055.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884668/
https://www.ncbi.nlm.nih.gov/pubmed/24141620
http://dx.doi.org/10.1261/rna.040055.113

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