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Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs
The mechanisms of gene expression regulation by miRNAs have been extensively studied. However, the regulation of miRNA function and decay has long remained enigmatic. Only recently, 3′ uridylation via LIN28A-TUT4/7 has been recognized as an essential component controlling the biogenesis of let-7 miR...
Autores principales: | Ustianenko, Dmytro, Hrossova, Dominika, Potesil, David, Chalupnikova, Katerina, Hrazdilova, Kristyna, Pachernik, Jiri, Cetkovska, Katerina, Uldrijan, Stjepan, Zdrahal, Zbynek, Vanacova, Stepanka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884668/ https://www.ncbi.nlm.nih.gov/pubmed/24141620 http://dx.doi.org/10.1261/rna.040055.113 |
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