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Lenalidomide at Therapeutic and Supratherapeutic Doses Does Not Prolong QTc Intervals in the Thorough QTc Study Conducted in Healthy Men

The effect of lenalidomide on the corrected QT (QTc) interval was evaluated in healthy men and extended to patients based on the lenalidomide concentration–QTc (C–QTc) relationship. A rigorous assessment of the effect of lenalidomide on QTc intervals was conducted in healthy volunteers who each rece...

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Detalles Bibliográficos
Autores principales: Chen, Nianhang, Ye, Ying, Liu, Liangang, Reyes, Josephine, Assaf, Mahmoud S, Kasserra, Claudia, Zhou, Simon, Palmisano, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884770/
https://www.ncbi.nlm.nih.gov/pubmed/23639045
http://dx.doi.org/10.1111/bcpt.12081