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Determination of antiprotozoal drug mechanisms by metabolomics approaches

The discovery, development and optimal utilization of pharmaceuticals can be greatly enhanced by knowledge of their modes of action. However, many drugs currently on the market act by unknown mechanisms. Untargeted metabolomics offers the potential to discover modes of action for drugs that perturb...

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Detalles Bibliográficos
Autores principales: CREEK, DARREN J., BARRETT, MICHAEL P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884841/
https://www.ncbi.nlm.nih.gov/pubmed/23734876
http://dx.doi.org/10.1017/S0031182013000814