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Sputum PGP is reduced by azithromycin treatment in patients with COPD and correlates with exacerbations

RATIONALE: Proline–glycine–proline (PGP), a neutrophil chemoattractant derived from the enzymatic breakdown of collagen, is elevated in sputum of patients with chronic obstructive pulmonary disease (COPD) and may contribute to disease progression. Whether sputum levels of PGP respond to therapy for...

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Detalles Bibliográficos
Autores principales: O'Reilly, Philip J, Jackson, Patricia L, Wells, J Michael, Dransfield, Mark T, Scanlon, Paul D, Blalock, J Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884851/
https://www.ncbi.nlm.nih.gov/pubmed/24366582
http://dx.doi.org/10.1136/bmjopen-2013-004140