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Lysine and Arginine Content of Proteins: Computational Analysis Suggests a New Tool for Solubility Design

[Image: see text] Prediction and engineering of protein solubility is an important but imprecise area. While some features are routinely used, such as the avoidance of extensive non-polar surface area, scope remains for benchmarking of sequence and structural features with experimental data. We stud...

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Detalles Bibliográficos
Autores principales: Warwicker, Jim, Charonis, Spyros, Curtis, Robin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885198/
https://www.ncbi.nlm.nih.gov/pubmed/24283752
http://dx.doi.org/10.1021/mp4004749