Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats

Curcumin is a bifunctional antioxidant derived from Curcuma longa. This study identifies curcumin as a neuroprotectant against hemin-induced damage in primary cultures of cerebellar granule neurons (CGNs) of rats. Hemin, the oxidized form of heme, is a highly reactive compound that induces cellular...

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Detalles Bibliográficos
Autores principales: González-Reyes, Susana, Guzmán-Beltrán, Silvia, Medina-Campos, Omar Noel, Pedraza-Chaverri, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885319/
https://www.ncbi.nlm.nih.gov/pubmed/24454990
http://dx.doi.org/10.1155/2013/801418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885319/
https://www.ncbi.nlm.nih.gov/pubmed/24454990
http://dx.doi.org/10.1155/2013/801418

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