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Global Gene Expression Analysis of Canine Osteosarcoma Stem Cells Reveals a Novel Role for COX-2 in Tumour Initiation

Osteosarcoma is the most common primary bone tumour of both children and dogs. It is an aggressive tumour in both species with a rapid clinical course leading ultimately to metastasis. In dogs and children distant metastasis occurs in >80% of individuals treated by surgery alone. Both canine and...

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Detalles Bibliográficos
Autores principales: Pang, Lisa Y., Gatenby, Emma L., Kamida, Ayako, Whitelaw, Bruce A., Hupp, Ted R., Argyle, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885401/
https://www.ncbi.nlm.nih.gov/pubmed/24416158
http://dx.doi.org/10.1371/journal.pone.0083144