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Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR3

Toll-like Receptor 3 (TLR3) is a pathogen pattern recognition receptor that plays a key role in innate immunity. TLR3 signalling has numerous functions in liver, both in health and disease. Here we report that TLR3 is expressed by quiescent hepatic stellate cells (HSC) where it functions to induce t...

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Detalles Bibliográficos
Autores principales: Wilson, Caroline L., Mann, Jelena, Walsh, Meagan, Perrugoria, Maria J., Oakley, Fiona, Wright, Matthew C., Brignole, Chiara, Di Paolo, Daniela, Perri, Patrizia, Ponzoni, Mirco, Karin, Michael, Mann, Derek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885413/
https://www.ncbi.nlm.nih.gov/pubmed/24416163
http://dx.doi.org/10.1371/journal.pone.0083391