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Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR3
Toll-like Receptor 3 (TLR3) is a pathogen pattern recognition receptor that plays a key role in innate immunity. TLR3 signalling has numerous functions in liver, both in health and disease. Here we report that TLR3 is expressed by quiescent hepatic stellate cells (HSC) where it functions to induce t...
Autores principales: | Wilson, Caroline L., Mann, Jelena, Walsh, Meagan, Perrugoria, Maria J., Oakley, Fiona, Wright, Matthew C., Brignole, Chiara, Di Paolo, Daniela, Perri, Patrizia, Ponzoni, Mirco, Karin, Michael, Mann, Derek A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885413/ https://www.ncbi.nlm.nih.gov/pubmed/24416163 http://dx.doi.org/10.1371/journal.pone.0083391 |
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