NPPB and ACAN, Two Novel SHOX2 Transcription Targets Implicated in Skeletal Development

SHOX and SHOX2 transcription factors are highly homologous, with even identical homeodomains. Genetic alterations in SHOX result in two skeletal dysplasias; Léri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD), while no human genetic disease has been linked to date with SHOX2. SHO...

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Detalles Bibliográficos
Autores principales: Aza-Carmona, Miriam, Barca-Tierno, Veronica, Hisado-Oliva, Alfonso, Belinchón, Alberta, Gorbenko-del Blanco, Darya, Rodriguez, Jose Ignacio, Benito-Sanz, Sara, Campos-Barros, Angel, Heath, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885427/
https://www.ncbi.nlm.nih.gov/pubmed/24421874
http://dx.doi.org/10.1371/journal.pone.0083104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885427/
https://www.ncbi.nlm.nih.gov/pubmed/24421874
http://dx.doi.org/10.1371/journal.pone.0083104

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