Variation of Pneumococcal Pilus-1 Expression Results in Vaccine Escape during Experimental Otitis Media [EOM]

The pneumococcal Pilus-1 enhances attachment to epithelial cells in the respiratory tract and subsequent invasion. Pilus-1 expression is bi-stable and positively regulated by the RlrA transcriptional regulator. To delineate the role of pilus-1 in Experimental Otitis Media (EOM), we evaluated coloniz...

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Detalles Bibliográficos
Autores principales: Figueira, Marisol, Moschioni, Monica, De Angelis, Gabriella, Barocchi, Michèle, Sabharwal, Vishakha, Masignani, Vega, Pelton, Stephen I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885439/
https://www.ncbi.nlm.nih.gov/pubmed/24421906
http://dx.doi.org/10.1371/journal.pone.0083798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885439/
https://www.ncbi.nlm.nih.gov/pubmed/24421906
http://dx.doi.org/10.1371/journal.pone.0083798

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