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Variation of Pneumococcal Pilus-1 Expression Results in Vaccine Escape during Experimental Otitis Media [EOM]
The pneumococcal Pilus-1 enhances attachment to epithelial cells in the respiratory tract and subsequent invasion. Pilus-1 expression is bi-stable and positively regulated by the RlrA transcriptional regulator. To delineate the role of pilus-1 in Experimental Otitis Media (EOM), we evaluated coloniz...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885439/ https://www.ncbi.nlm.nih.gov/pubmed/24421906 http://dx.doi.org/10.1371/journal.pone.0083798 |