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Antibody Responses to a Novel Plasmodium falciparum Merozoite Surface Protein Vaccine Correlate with Protection against Experimental Malaria Infection in Aotus Monkeys

The Block 2 region of the merozoite surface protein-1 (MSP-1) of Plasmodium falciparum has been identified as a target of protective immunity by a combination of seroepidemiology and parasite population genetics. Immunogenicity studies in small animals and Aotus monkeys were used to determine the ef...

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Detalles Bibliográficos
Autores principales: Cavanagh, David R., Kocken, Clemens H. M., White, John H., Cowan, Graeme J. M., Samuel, Kay, Dubbeld, Martin A., der Wel, Annemarie Voorberg-van, Thomas, Alan W., McBride, Jana S., Arnot, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885447/
https://www.ncbi.nlm.nih.gov/pubmed/24421900
http://dx.doi.org/10.1371/journal.pone.0083704