Transposon Mutagenesis of Probiotic Lactobacillus casei Identifies asnH, an Asparagine Synthetase Gene Involved in Its Immune-Activating Capacity

Lactobacillus casei ATCC 27139 enhances host innate immunity, and the J1 phage-resistant mutants of this strain lose the activity. A transposon insertion mutant library of L. casei ATCC 27139 was constructed, and nine J1 phage-resistant mutants out of them were obtained. Cloning and sequencing analy...

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Detalles Bibliográficos
Autores principales: Ito, Masahiro, Kim, Yun-Gi, Tsuji, Hirokazu, Takahashi, Takuya, Kiwaki, Mayumi, Nomoto, Koji, Danbara, Hirofumi, Okada, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885529/
https://www.ncbi.nlm.nih.gov/pubmed/24416179
http://dx.doi.org/10.1371/journal.pone.0083876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885529/
https://www.ncbi.nlm.nih.gov/pubmed/24416179
http://dx.doi.org/10.1371/journal.pone.0083876

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