Cargando…

Transposon Mutagenesis of Probiotic Lactobacillus casei Identifies asnH, an Asparagine Synthetase Gene Involved in Its Immune-Activating Capacity

Lactobacillus casei ATCC 27139 enhances host innate immunity, and the J1 phage-resistant mutants of this strain lose the activity. A transposon insertion mutant library of L. casei ATCC 27139 was constructed, and nine J1 phage-resistant mutants out of them were obtained. Cloning and sequencing analy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ito, Masahiro, Kim, Yun-Gi, Tsuji, Hirokazu, Takahashi, Takuya, Kiwaki, Mayumi, Nomoto, Koji, Danbara, Hirofumi, Okada, Nobuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885529/ https://www.ncbi.nlm.nih.gov/pubmed/24416179 http://dx.doi.org/10.1371/journal.pone.0083876

Ejemplares similares

Novel Mutations in the Asparagine Synthetase Gene (ASNS) Associated With Microcephaly
por: Schleinitz, Dorit, et al.
Publicado: (2018)

A method for measurement of human asparagine synthetase (ASNS) activity and application to ASNS protein variants associated with ASNS deficiency
por: Chang, Mario C, et al.
Publicado: (2023)

Saccharomyces cerevisiae ASN1 and ASN2 are asparagine synthetase paralogs that have diverged in their ability to polymerize in response to nutrient stress
por: Noree, Chalongrat, et al.
Publicado: (2019)

A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency
por: Wang, Chun, et al.
Publicado: (2020)

Wheat with greatly reduced accumulation of free asparagine in the grain, produced by CRISPR/Cas9 editing of asparagine synthetase gene TaASN2
por: Raffan, Sarah, et al.
Publicado: (2021)

Case report: A compound heterozygous mutations in ASNS broadens the spectrum of asparagine synthetase deficiency in the prenatal diagnosis
por: Zhu, Linyan, et al.
Publicado: (2023)

Cereal asparagine synthetase genes
por: Raffan, Sarah, et al.
Publicado: (2020)

Reduced free asparagine in wheat grain resulting from a natural deletion of TaASN-B2: investigating and exploiting diversity in the asparagine synthetase gene family to improve wheat quality
por: Oddy, Joseph, et al.
Publicado: (2021)

Cellular and molecular characterization of two novel asparagine synthetase gene mutations linked to asparagine synthetase deficiency
por: Staklinski, Stephen J., et al.
Publicado: (2022)

Knockdown of Asparagine Synthetase A Renders Trypanosoma brucei Auxotrophic to Asparagine
por: Loureiro, Inês, et al.
Publicado: (2013)

Filamentation of asparagine synthetase in Saccharomyces cerevisiae
por: Zhang, Shanshan, et al.
Publicado: (2018)

Correction: Knockdown of Asparagine Synthetase A Renders Trypanosoma brucei Auxotrophic to Asparagine
por: Loureiro, Inês, et al.
Publicado: (2013)

Metabolomic Profiling of Asparagine Deprivation in Asparagine Synthetase Deficiency Patient-Derived Cells
por: Chang, Mario C., et al.
Publicado: (2023)

Novel Insights into Regulation of Asparagine Synthetase in Conifers
por: Canales, Javier, et al.
Publicado: (2012)

Human asparagine synthetase associates with the mitotic spindle
por: Noree, Chalongrat, et al.
Publicado: (2018)

Coordination of asparagine uptake and asparagine synthetase expression modulates CD8(+) T cell activation
por: Hope, Helen Carrasco, et al.
Publicado: (2021)

OsASN1 Plays a Critical Role in Asparagine-Dependent Rice Development
por: Luo, Le, et al.
Publicado: (2018)

Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia
por: Chiu, Martina, et al.
Publicado: (2020)

Development of an Escherichia coli–Lactobacillus casei shuttle vector for heterologous protein expression in Lactobacillus casei
por: Suebwongsa, Namfon, et al.
Publicado: (2016)

Analysis of Enzyme Activity and Cellular Function for the N80S and S480F Asparagine Synthetase Variants Expressed in a Child with Asparagine Synthetase Deficiency
por: Staklinski, Stephen J., et al.
Publicado: (2022)

New Genes Involved in Mild Stress Response Identified by Transposon Mutagenesis in Lactobacillus paracasei
por: Palud, Aurore, et al.
Publicado: (2018)

Transposon mutagenesis in oral streptococcus
por: Zhang, Yixin, et al.
Publicado: (2022)

Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression
por: Grima-Reyes, Manuel, et al.
Publicado: (2022)

Genomic, Biochemical, and Modeling Analyses of Asparagine Synthetases from Wheat
por: Xu, Hongwei, et al.
Publicado: (2018)

Characterizing asparagine synthetase deficiency variants in lymphoblastoid cell lines
por: Staklinski, Stephen J., et al.
Publicado: (2023)

Severe Microcephaly and Metabolic Epilepsy due to Asparagine Synthetase Deficiency
por: Saini, Arushi G., et al.
Publicado: (2023)

Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma
por: Fu, Yong, et al.
Publicado: (2021)

Genomic Adaptation of the Lactobacillus casei Group
por: Toh, Hidehiro, et al.
Publicado: (2013)

Identification and Classification for the Lactobacillus casei Group
por: Huang, Chien-Hsun, et al.
Publicado: (2018)

Clinical outcomes of two patients with a novel pathogenic variant in ASNS: response to asparagine supplementation and review of the literature
por: Sprute, Rosanne, et al.
Publicado: (2019)

Food safety: Structure and expression of the asparagine synthetase gene family of wheat
por: Gao, Runhong, et al.
Publicado: (2016)

Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity
por: Faria, Joana, et al.
Publicado: (2016)

Functional Research on Three Presumed Asparagine Synthetase Family Members in Poplar
por: Qu, Chunpu, et al.
Publicado: (2019)

Polymorphism in asparagine synthetase is associated with overall survival of hepatocellular carcinoma patients
por: Li, Wei, et al.
Publicado: (2017)

Asparagine Synthetase and Filamin A Have Different Roles in Ovarian Cancer
por: Zeng, Liang, et al.
Publicado: (2019)

Asparagine synthetase deficiency: A novel case with an unusual molecular mechanism
por: Faoucher, Marie, et al.
Publicado: (2019)

Primary cilia sense glutamine availability and respond via asparagine synthetase
por: Steidl, Maria Elena, et al.
Publicado: (2023)

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
por: Xie, Stanley C., et al.
Publicado: (2023)

Utility of AlphaMissense predictions in Asparagine Synthetase deficiency variant classification
por: Staklinski, Stephen J., et al.
Publicado: (2023)

Formation of gold nanoparticles by glycolipids of Lactobacillus casei
por: Kikuchi, Fumiya, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_okjmls1muhtlbqajal8qnjj4v4