Perivascular Delivery of Notch 1 siRNA Inhibits Injury-Induced Arterial Remodeling

OBJECTIVES: To determine the efficacy of perivascular delivery of Notch 1 siRNA in preventing injury-induced arterial remodeling. METHODS AND RESULTS: Carotid artery ligation was performed to induce arterial remodeling. After 14 days, morphometric analysis confirmed increased vSMC growth and subsequ...

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Detalles Bibliográficos
Autores principales: Redmond, Eileen M., Liu, Weimin, Hamm, Katie, Hatch, Ekaterina, Cahill, Paul A., Morrow, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885538/
https://www.ncbi.nlm.nih.gov/pubmed/24416200
http://dx.doi.org/10.1371/journal.pone.0084122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885538/
https://www.ncbi.nlm.nih.gov/pubmed/24416200
http://dx.doi.org/10.1371/journal.pone.0084122

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