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Perivascular Delivery of Notch 1 siRNA Inhibits Injury-Induced Arterial Remodeling
OBJECTIVES: To determine the efficacy of perivascular delivery of Notch 1 siRNA in preventing injury-induced arterial remodeling. METHODS AND RESULTS: Carotid artery ligation was performed to induce arterial remodeling. After 14 days, morphometric analysis confirmed increased vSMC growth and subsequ...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885538/ https://www.ncbi.nlm.nih.gov/pubmed/24416200 http://dx.doi.org/10.1371/journal.pone.0084122 |