Depletion of Sirtuin 1 (SIRT1) Leads to Epigenetic Modifications of Telomerase (TERT) Gene in Hepatocellular Carcinoma Cells

Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase that is implicated in plethora of biological processes, including metabolism, aging, stress response, and tumorigenesis. Telomerase (TERT) is essential for telomere maintenance. Activation of TERT is considered a cr...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Chen, Juan, Cheng, Alfred S. L., Ko, Ben C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885646/
https://www.ncbi.nlm.nih.gov/pubmed/24416313
http://dx.doi.org/10.1371/journal.pone.0084931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885646/
https://www.ncbi.nlm.nih.gov/pubmed/24416313
http://dx.doi.org/10.1371/journal.pone.0084931

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