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Age-Dependent Relevance of Endogenous 5-Lipoxygenase Derivatives in Anxiety-Like Behavior in Mice
When 5-lipoxygenase (5-LO) is inhibited, roughly half of the CNS effect of the prototypic endocannabinoid anandamide (AEA) is lost. Therefore, we decided to investigate whether inhibiting this enzyme would influence physiological functions classically described as being under control of the endocann...
Autores principales: | Leo, Luciana M., Almeida-Corrêa, Suellen, Canetti, Claudio A., Amaral, Olavo B., Bozza, Fernando A., Pamplona, Fabricio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885659/ https://www.ncbi.nlm.nih.gov/pubmed/24416334 http://dx.doi.org/10.1371/journal.pone.0085009 |
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