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GEC-derived SFRP5 Inhibits Wnt5a-Induced Macrophage Chemotaxis and Activation

Aberrant macrophage infiltration and activation has been implicated in gastric inflammation and carcinogenesis. Overexpression of Wnt5a and downregulation of SFRP5, a Wnt5a antagonist, were both observed in gastric cancers recently. This study attempted to explore whether Wnt5a/SFRP5 axis was involv...

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Detalles Bibliográficos
Autores principales: Zhao, Chenghai, Bu, Xianmin, Wang, Wei, Ma, Tingxian, Ma, Haiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885681/
https://www.ncbi.nlm.nih.gov/pubmed/24416340
http://dx.doi.org/10.1371/journal.pone.0085058