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GEC-derived SFRP5 Inhibits Wnt5a-Induced Macrophage Chemotaxis and Activation
Aberrant macrophage infiltration and activation has been implicated in gastric inflammation and carcinogenesis. Overexpression of Wnt5a and downregulation of SFRP5, a Wnt5a antagonist, were both observed in gastric cancers recently. This study attempted to explore whether Wnt5a/SFRP5 axis was involv...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885681/ https://www.ncbi.nlm.nih.gov/pubmed/24416340 http://dx.doi.org/10.1371/journal.pone.0085058 |