Cargando…
GEC-derived SFRP5 Inhibits Wnt5a-Induced Macrophage Chemotaxis and Activation
Aberrant macrophage infiltration and activation has been implicated in gastric inflammation and carcinogenesis. Overexpression of Wnt5a and downregulation of SFRP5, a Wnt5a antagonist, were both observed in gastric cancers recently. This study attempted to explore whether Wnt5a/SFRP5 axis was involv...
Autores principales: | Zhao, Chenghai, Bu, Xianmin, Wang, Wei, Ma, Tingxian, Ma, Haiying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885681/ https://www.ncbi.nlm.nih.gov/pubmed/24416340 http://dx.doi.org/10.1371/journal.pone.0085058 |
Ejemplares similares
-
Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer
por: Zhao, Chenghai, et al.
Publicado: (2009) -
IL-1β mediates MCP-1 induction by Wnt5a in gastric cancer cells
por: Li, Shengjun, et al.
Publicado: (2014) -
SFRP5 inhibits the migration and invasion of melanoma cells through Wnt signaling pathway
por: Chen, Yangmei, et al.
Publicado: (2018) -
SFRP5 inhibits melanin synthesis of melanocytes in vitiligo by suppressing the Wnt/β-catenin signaling
por: Zou, Dao-Pei, et al.
Publicado: (2020) -
SFRP5 Enhances Wnt5a Induced-Inflammation in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
por: Mahmoud, Dorra Elhaj, et al.
Publicado: (2021)