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Cell Surface-Associated Anti-MUC1-Derived Signal Peptide Antibodies: Implications for Cancer Diagnostics and Therapy

The MUC1 tumor associated antigen is highly expressed on a range of tumors. Its broad distribution on primary tumors and metastases renders it an attractive target for immunotherapy. After synthesis MUC1 is cleaved, yielding a large soluble extracellular alpha subunit containing the tandem repeats a...

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Detalles Bibliográficos
Autores principales: Kovjazin, Riva, Horn, Galit, Smorodinsky, Nechama I., Shapira, Michael Y., Carmon, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885691/
https://www.ncbi.nlm.nih.gov/pubmed/24416403
http://dx.doi.org/10.1371/journal.pone.0085400