Roflumilast N-Oxide Prevents Cytokine Secretion Induced by Cigarette Smoke Combined with LPS through JAK/STAT and ERK1/2 Inhibition in Airway Epithelial Cells

Cigarette smoke is a major cause of chronic obstructive pulmonary disease (COPD). Airway epithelial cells and macrophages are the first defense cells against cigarette smoke and these cells are an important source of pro-inflammatory cytokines. These cytokines play a role in progressive airflow limi...

Descripción completa

Detalles Bibliográficos
Autores principales: Victoni, Tatiana, Gleonnec, Florence, Lanzetti, Manuella, Tenor, Hermann, Valença, Samuel, Porto, Luis Cristovão, Lagente, Vincent, Boichot, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885699/
https://www.ncbi.nlm.nih.gov/pubmed/24416369
http://dx.doi.org/10.1371/journal.pone.0085243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885699/
https://www.ncbi.nlm.nih.gov/pubmed/24416369
http://dx.doi.org/10.1371/journal.pone.0085243

Ejemplares similares