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Neuroprotective Effects of a Novel Single Compound 1-Methoxyoctadecan-1-ol Isolated from Uncaria sinensis in Primary Cortical Neurons and a Photothrombotic Ischemia Model

We identified a novel neuroprotective compound, 1-methoxyoctadecan-1-ol, from Uncaria sinensis (Oliv.) Havil and investigated its effects and mechanisms in primary cortical neurons and in a photothrombotic ischemic model. In primary rat cortical neurons against glutamate-induced neurotoxicity, pretr...

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Detalles Bibliográficos
Autores principales: Jang, Ji Yeon, Choi, Young Whan, Kim, Ha Neui, Kim, Yu Ri, Hong, Jin Woo, Bae, Dong Won, Park, Se Jin, Shin, Hwa Kyoung, Choi, Byung Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885700/
https://www.ncbi.nlm.nih.gov/pubmed/24416390
http://dx.doi.org/10.1371/journal.pone.0085322