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A Majority of Human Melanoma Cell Lines Exhibits an S Phase-Specific Defect in Excision of UV-Induced DNA Photoproducts

It is well established that efficient removal of highly-promutagenic UV-induced dipyrimidine photoproducts via nucleotide excision repair (NER) is required for protection against sunlight-associated malignant melanoma. Nonetheless, the extent to which reduced NER capacity might contribute to individ...

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Detalles Bibliográficos
Autores principales: Bélanger, François, Rajotte, Vincent, Drobetsky, Elliot A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885708/
https://www.ncbi.nlm.nih.gov/pubmed/24416382
http://dx.doi.org/10.1371/journal.pone.0085294