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A Genetic Variant in the Promoter Region of miR-106b-25 Cluster Predict Clinical Outcome of HBV-Related Hepatocellular Carcinoma in Chinese

BACKGROUND: MiR-106b-25 cluster, hosted in intron 13 of MCM7, may play integral roles in diverse processes including immune response, tumorigenesis and progression. A single nucleotide polymorphism (SNP), rs999885, is located in the promoter region of MCM7. Our previous study showed that the A to G...

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Detalles Bibliográficos
Autores principales: Qi, Fuzhen, Huang, Mingde, Pan, Yun, Liu, Yao, Liu, Jibin, Wen, Juan, Xie, Kaipeng, Shen, Hongbing, Ma, Hongxia, Miao, Yi, Hu, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885710/
https://www.ncbi.nlm.nih.gov/pubmed/24416400
http://dx.doi.org/10.1371/journal.pone.0085394