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Resveratrol Induces Vascular Smooth Muscle Cell Differentiation through Stimulation of SirT1 and AMPK

Phenotypic plasticity in vascular smooth muscle cells (VSMC) is necessary for vessel maintenance, repair and adaptation to vascular changes associated with aging. De-differentiated VSMC contribute to pathologies including atherosclerosis and intimal hyperplasia. As resveratrol has been reported to h...

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Detalles Bibliográficos
Autores principales: Thompson, Anne Marie, Martin, Kathleen A., Rzucidlo, Eva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885718/
https://www.ncbi.nlm.nih.gov/pubmed/24416418
http://dx.doi.org/10.1371/journal.pone.0085495