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TL1A Induces TCR Independent IL-6 and TNF-α Production and Growth of PLZF(+) Leukocytes

An elevated level of the cytokine TL1A is known to be associated with several autoimmune diseases, e.g. rheumatoid arthritis and inflammatory bowel disease. However, the mode of action of TL1A remains elusive. In this study, we investigated the role of TL1A in a pro-inflammatory setting, using human...

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Detalles Bibliográficos
Autores principales: Reichwald, Kirsten, Jørgensen, Tina Z., Tougaard, Peter, Skov, Søren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885722/
https://www.ncbi.nlm.nih.gov/pubmed/24416448
http://dx.doi.org/10.1371/journal.pone.0085793