GILT: Shaping the MHC Class II-Restricted Peptidome and CD4(+) T Cell-Mediated Immunity

The MHC class II-restricted antigen processing pathway generates peptide:MHC complexes in the endocytic pathway for the activation of CD4(+) T cells. Gamma-interferon-inducible lysosomal thiol reductase (GILT) reduces protein disulfide bonds in the endocytic compartment, thereby exposing buried epit...

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Detalles Bibliográficos
Autor principal: Hastings, Karen Taraszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885806/
https://www.ncbi.nlm.nih.gov/pubmed/24409178
http://dx.doi.org/10.3389/fimmu.2013.00429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885806/
https://www.ncbi.nlm.nih.gov/pubmed/24409178
http://dx.doi.org/10.3389/fimmu.2013.00429

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