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Animal Models to Study the Mutational Landscape for Oral Cavity and Oropharyngeal Cancers

OBJECTIVES: Cancer is likely caused by alterations in gene structure or expression. Recently, next generation sequencing has documented mutations in 106 head and neck squamous cell cancer genomes, suggesting several new candidate genes. However, it remains difficult to determine which mutations dire...

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Detalles Bibliográficos
Autores principales: Spiotto, Michael T., Pytynia, Matthew, Liu, Gene-Fu F., Ranck, Mark C., Widau, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Stilus Optimus 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886108/
https://www.ncbi.nlm.nih.gov/pubmed/24422024
http://dx.doi.org/10.5037/jomr.2013.4101