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Heavy Water Reduces GFP Expression in Prokaryotic Cell-Free Assays at the Translation Level While Stimulating Its Transcription

The in vitro proliferation of prokaryotic and eukaryotic cells is remarkably hampered in the presence of heavy water (D(2)O). Impairment of gene expression at the transcription or translation level can be the base for this effect. However, insights into the underlying mechanisms are lacking. Here, w...

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Detalles Bibliográficos
Autores principales: Hohlefelder, Luisa S., Stögbauer, Tobias, Opitz, Madeleine, Bayerl, Thomas M., Rädler, Joachim O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886400/
https://www.ncbi.nlm.nih.gov/pubmed/24455706
http://dx.doi.org/10.1155/2013/592745