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Randomized, double-blind, placebo-controlled and active-controlled study to assess the relative abuse potential of oxycodone HCl-niacin tablets compared with oxycodone alone in nondependent, recreational opioid users

BACKGROUND: Abuse-deterrent formulations attempt to address public health and societal concerns regarding opioid abuse. Oxycodone HCl-niacin tablets combine oxycodone HCl with niacin and functional inactive excipients to create potential barriers to oral, intranasal, and intravenous abuse. This stud...

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Detalles Bibliográficos
Autores principales: Webster, Lynn R, Rolleri, Robert L, Pixton, Glenn C, Sommerville, Kenneth W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886648/
https://www.ncbi.nlm.nih.gov/pubmed/24474870
http://dx.doi.org/10.2147/SAR.S33080