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Flank Sequences of miR‐145/143 and Their Aberrant Expression in Vascular Disease: Mechanism and Therapeutic Application

BACKGROUND: Many microRNAs (miRNAs) are downregulated in proliferative vascular disease. Thus, upregulation of these miRNAs has become a major focus of research activity. However, there is a critical barrier in gene therapy to upregulate some miRNAs such as miR‐145 and miR‐143 because of their signi...

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Detalles Bibliográficos
Autores principales: Liu, Xiaojun, Cheng, Yunhui, Yang, Jian, Qin, Shanshan, Chen, Xiuwei, Tang, Xiaojun, Zhou, Xiangyu, Krall, Thomas J., Zhang, Chunxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886745/
https://www.ncbi.nlm.nih.gov/pubmed/24166492
http://dx.doi.org/10.1161/JAHA.113.000407