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Activation of Hypoxia‐Inducible Factor‐2 in Adipocytes Results in Pathological Cardiac Hypertrophy

BACKGROUND: Obesity can cause structural and functional abnormalities of the heart via complex but largely undefined mechanisms. Emerging evidence has shown that obesity results in reduced oxygen concentrations, or hypoxia, in adipose tissue. We hypothesized that the adipocyte hypoxia‐signaling path...

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Detalles Bibliográficos
Autores principales: Lin, Qun, Huang, Yan, Booth, Carmen J., Haase, Volker H., Johnson, Randall S., Celeste Simon, M., Giordano, Frank J., Yun, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886757/
https://www.ncbi.nlm.nih.gov/pubmed/24326162
http://dx.doi.org/10.1161/JAHA.113.000548