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Activation of Hypoxia‐Inducible Factor‐2 in Adipocytes Results in Pathological Cardiac Hypertrophy
BACKGROUND: Obesity can cause structural and functional abnormalities of the heart via complex but largely undefined mechanisms. Emerging evidence has shown that obesity results in reduced oxygen concentrations, or hypoxia, in adipose tissue. We hypothesized that the adipocyte hypoxia‐signaling path...
Autores principales: | Lin, Qun, Huang, Yan, Booth, Carmen J., Haase, Volker H., Johnson, Randall S., Celeste Simon, M., Giordano, Frank J., Yun, Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886757/ https://www.ncbi.nlm.nih.gov/pubmed/24326162 http://dx.doi.org/10.1161/JAHA.113.000548 |
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