p53 and TAp63 Promote Keratinocyte Proliferation and Differentiation in Breeding Tubercles of the Zebrafish

p63 is a multi-isoform member of the p53 family of transcription factors. There is compelling genetic evidence that ΔNp63 isoforms are needed for keratinocyte proliferation and stemness in the developing vertebrate epidermis. However, the role of TAp63 isoforms is not fully understood, and TAp63 kno...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischer, Boris, Metzger, Manuel, Richardson, Rebecca, Knyphausen, Philipp, Ramezani, Thomas, Franzen, Rainer, Schmelzer, Elmon, Bloch, Wilhelm, Carney, Thomas J., Hammerschmidt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886889/
https://www.ncbi.nlm.nih.gov/pubmed/24415949
http://dx.doi.org/10.1371/journal.pgen.1004048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886889/
https://www.ncbi.nlm.nih.gov/pubmed/24415949
http://dx.doi.org/10.1371/journal.pgen.1004048

Ejemplares similares