Deletion of a Conserved cis-Element in the Ifng Locus Highlights the Role of Acute Histone Acetylation in Modulating Inducible Gene Transcription

Differentiation-dependent regulation of the Ifng cytokine gene locus in T helper (Th) cells has emerged as an excellent model for functional study of distal elements that control lineage-specific gene expression. We previously identified a cis-regulatory element located 22 kb upstream of the Ifng ge...

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Detalles Bibliográficos
Autores principales: Balasubramani, Anand, Winstead, Colleen J., Turner, Henrietta, Janowski, Karen M., Harbour, Stacey N., Shibata, Yoichiro, Crawford, Gregory E., Hatton, Robin D., Weaver, Casey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886902/
https://www.ncbi.nlm.nih.gov/pubmed/24415943
http://dx.doi.org/10.1371/journal.pgen.1003969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886902/
https://www.ncbi.nlm.nih.gov/pubmed/24415943
http://dx.doi.org/10.1371/journal.pgen.1003969

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