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Orally Active Antischistosomal Early Leads Identified from the Open Access Malaria Box

BACKGROUND: Worldwide hundreds of millions of schistosomiasis patients rely on treatment with a single drug, praziquantel. Therapeutic limitations and the threat of praziquantel resistance underline the need to discover and develop next generation drugs. METHODOLOGY: We studied the antischistosomal...

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Detalles Bibliográficos
Autores principales: Ingram-Sieber, Katrin, Cowan, Noemi, Panic, Gordana, Vargas, Mireille, Mansour, Nuha R., Bickle, Quentin D., Wells, Timothy N. C., Spangenberg, Thomas, Keiser, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886923/
https://www.ncbi.nlm.nih.gov/pubmed/24416463
http://dx.doi.org/10.1371/journal.pntd.0002610