HIF-1alpha Expression Profile in Intratumoral and Peritumoral Inflammatory Cells as a Prognostic Marker for Squamous Cell Carcinoma of the Oral Cavity

The HIF-1 transcriptional complex is responsible for controlling transcription of over 100 genes involved in cell hypoxia response. HIF-1alpha subunit is stabilized in hypoxia conditions, creating the HIF-1 nuclear transcription factor. In inflammatory cells, high HIF-1alpha expression induces lymph...

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Detalles Bibliográficos
Autores principales: Mendes, Suzanny Oliveira, dos Santos, Marcelo, Peterle, Gabriela Tonini, Maia, Lucas de Lima, Stur, Elaine, Agostini, Lidiane Pignaton, de Carvalho, Marcos Brasilino, Tajara, Eloiza Helena, Louro, Iúri Drumond, Trivilin, Leonardo Oliveira, da Silva-Conforti, Adriana Madeira Álvares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887011/
https://www.ncbi.nlm.nih.gov/pubmed/24416312
http://dx.doi.org/10.1371/journal.pone.0084923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887011/
https://www.ncbi.nlm.nih.gov/pubmed/24416312
http://dx.doi.org/10.1371/journal.pone.0084923

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