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Profound Morphological Changes in the Erythrocytes and Fibrin Networks of Patients with Hemochromatosis or with Hyperferritinemia, and Their Normalization by Iron Chelators and Other Agents

It is well-known that individuals with increased iron levels are more prone to thrombotic diseases, mainly due to the presence of unliganded iron, and thereby the increased production of hydroxyl radicals. It is also known that erythrocytes (RBCs) may play an important role during thrombotic events....

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Detalles Bibliográficos
Autores principales: Pretorius, Etheresia, Bester, Janette, Vermeulen, Natasha, Lipinski, Boguslaw, Gericke, George S., Kell, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887013/
https://www.ncbi.nlm.nih.gov/pubmed/24416376
http://dx.doi.org/10.1371/journal.pone.0085271