SPBP Is a Sulforaphane Induced Transcriptional Coactivator of NRF2 Regulating Expression of the Autophagy Receptor p62/SQSTM1

Organisms exposed to oxidative stress respond by orchestrating a stress response to prevent further damage. Intracellular levels of antioxidant agents increase, and damaged components are removed by autophagy induction. The KEAP1-NRF2 signaling pathway is the main pathway responsible for cell defens...

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Detalles Bibliográficos
Autores principales: Darvekar, Sagar Ramesh, Elvenes, Julianne, Brenne, Hanne Britt, Johansen, Terje, Sjøttem, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887019/
https://www.ncbi.nlm.nih.gov/pubmed/24416372
http://dx.doi.org/10.1371/journal.pone.0085262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887019/
https://www.ncbi.nlm.nih.gov/pubmed/24416372
http://dx.doi.org/10.1371/journal.pone.0085262

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