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Effect of Wild-Type Shigella Species and Attenuated Shigella Vaccine Candidates on Small Intestinal Barrier Function, Antigen Trafficking, and Cytokine Release

Bacterial dysentery due to Shigella species is a major cause of morbidity and mortality worldwide. The pathogenesis of Shigella is based on the bacteria's ability to invade and replicate within the colonic epithelium, resulting in severe intestinal inflammatory response and epithelial destructi...

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Detalles Bibliográficos
Autores principales: Fiorentino, Maria, Levine, Myron M., Sztein, Marcelo B., Fasano, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887025/
https://www.ncbi.nlm.nih.gov/pubmed/24416363
http://dx.doi.org/10.1371/journal.pone.0085211